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The G/G genotype was observed in 12.9% of individuals with T2DM and in 11.4% of controls (p = 0.036)

For instance, exposure to H 2 O 2 led to a redistribution of ZO-1 from the TJs to the cytosol, resulting in a decrease in transepithelial electrical resistance (TEER) and an increase in BBB permeability ( 91 phox of NOX2 weakened the BBB damage induced by ischemic stroke in gp 91 phox -deficient mice to a great extent compared with wild-type mice ( 91 phox deficient mice is likely the result of less induction of MMP-9 and reduced loss of occludin, a critical TJs of the BBB (Van der Goes et al., 2001

Glutathione is the most powerful antioxidant produced by the body

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