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doi: 10.1074/jbc.M11189920

The liver is the bodys primary detoxification organ, and glutathione plays a vital role in the livers ability to neutralize and eliminate toxins, free radicals, and waste products

Due to this enzymatic reaction, a variety of glucosinolate hydrolysis products (GHPs) can be generated such as isothiocyanates (ITCs), nitriles, epithionitriles and thiocyanates depending on the GSL substrate and reaction conditions 3

Compared to FoB, MZB were previously shown to use GSH through Gpx4 for protection from excessive lipid peroxidation 33 , suggesting a differential dependency on redox functions downstream of GSH synthesis