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Metabolic reprogramming during hyperammonemia targets mitochondrial function and postmitotic senescence

NA cells were mock treated or treated with MNNG (1g/ml) for 24 h and then harvested for Co-IP assay using mouse monoclonal antibodies against p53, Sp1, or mouse IgG as a control

Even with normal blood levels, some people benefit from B12 injections

Although the level of vitamin B12 may be reduced in advanced patients, higher vitamin B12 levels indicate a higher risk of cirrhosis transformation (143), which brings new challenges to vitamin B12 alone