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doi: 10.1159/000104236 30 TharmalingamJGangadaranPRajendranRLAhnBC

A further study examined whether SAMe could delay neuropathology in 3Tg-AD mice, which harbor mutant genes for human APP, PS-1, and tau, here showing that SAMe supplementation in the diet did, in fact, reduce extracellular A deposits [196]