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DIAGNOSIS AND CONTRIBUTING FACTORS The typical presentation of LAST usually begins with prodromal symptoms and signs, such as perioral numbness, tinnitus, agitation, dysarthria, and confusion

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Deciding which measure of density to use in oceanographic analyses can be challenging, and is still an area of ongoing research.

Other less common forms of CMegA include thiamine-responsive megaloblastic anemia syndrome with diabetes and deafness (118), defective cobalamin synthesis associated with hemolytic-uremic syndrome (119), hereditary transcobalamin II deficiency (120), and other rare inborn errors of metabolism (121,122), including mitochrondrial cytopathy (123)