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and SOD, which converts superoxide anions into hydrogen peroxide as a substrate for catalase [20]

Other research has pointed to vitreous liquefaction as being responsible for approximately 15% to 20% of primary open-angle glaucoma cases.3,4 As noted above, the vitreous gel consumes oxygen in an ascorbate-dependent manner, but the crystalline lens itself also consumes oxygen using mitochondria in the lens epithelium and reduced glutathione in the lens cortex

Kynurenine Pathway of Tryptophan Metabolism: Regulatory and Functional Aspects

Nevertheless, the combination of Cur and CDDP resulted in a greater upregulation of these proteins associated with apoptosis, indicating that Cur enhanced the effect of CDDP on inducing cell death