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Flavonoids also possess anticancer activity, which has been shown to go beyond the antioxidant, free radical-scavenging activity, but may involve mechanisms such as regulation of gene expression in cell proliferation, oncogenes and tumour suppressor genes, induction of cell cycle arrest and apoptosis, modulation of detoxification enzymes activity, stimulation of immune system and regulation of hormone metabolism [165]

PLoS ONE 19 (4), e0301454

The efficacy of hGH was confirmed by these experiments as, 6 days after initiation of treatment, greater numbers of apoptotic cells (Figure 5A) and cells displaying NF- B inhibition (Figure 5B) were observed in mice treated with both drug and rhGH than in the other groups of mice

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