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ALS is mostly diagnosed based on clinical signs, using the revised El Escorial criteria, which require signs of both upper motor neuron (e.g., spasticity, brisk reflexes) and lower motor neuron damage (e.g., muscle wasting, twitching) in multiple body regions (Brotman et al., 2025)

Lips Effect Duration: up to 1 year Just as with other areas of our faces, our lips lose fullness and smoothness as we age

Table: Quick Comparison Feature IV: Therapy Oral Supplements Absorption Immediate Delayed Speed 24 weeks, 13 months Convenience requires appointments, At-home use Cost is High, more budget-friendly Choosing the right option depends on how quickly you want results, your comfort with clinical procedures, and your budget

This concept, called tumor angiogenesis, has driven an entire class of cancer drugs (anti-angiogenics like bevacizumab)