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Additionally, the use of a wide range of AOXs (either single or in combinations) and the lack of standardized dosages in different studies preclude the ability to draw a firm conclusion on the efficacy of AOX supplementation in solving infertility problem

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The results revealed statistically significant mean differences in C-reactive protein serum levels between groups at 24 h postadjunctive therapy with melatonin and a significant improvement of clinical condition in neonates from the intervention group compared to the control group within 3 days of therapy 109

The lack of equitable access, behavioral and cultural change, regulation of quality of commercial products and methodological fortification of the evidence base are rather numerous issues that are to be solved yet they can be addressed in collaboration of the research, policy, industry and civil society