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Given the apparently similar affinity of corynantheidine and ajmalicine at 5-HT 1A Rs to the alkaloids evaluated here (Table 1), future in vitro 5-HT 1A R and in vivo lower lip retraction studies with these two alkaloids may also be warranted

During a copper-deficient state, the copper deficiency leads to mitochondrial dysfunction and ROS accumulation, which in-turn lead to cardiovascular diseases including myocardial I/R injury (94)

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