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Images corresponding to each sample were averaged to obtain the mean adipocyte area (m2) per sample and combined to calculate group mean values for control (vehicle-treated EWAT samples) and treatment (NNMT inhibitor-treated EWAT samples) cohorts

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Patients should understand that such treatments are not substitutes for evidence-based weight management strategies endorsed by NICE, including dietary modification, physical activity, andwhere appropriatelicensed pharmacotherapy