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However, it is very likely that, since estimated risk is based on tumour incidence at concentrations that induce irritancy in the respiratory tract and no-observed-effect levels for irritancy are well below these concentrations, the true cancer risk is most likely much lower at concentrations generally present in the environment and may, indeed, be zero

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Lifetime carcinogenicity studies with oral aripiprazole have been conducted in ICR mice and in Sprague-Dawley (SD) and F344 rats

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