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117 Additionally, to improve patient compliance, it is crucial to extend the drugs half-life

GHK-Cu has one of the most extensively studied gene expression profiles of any peptide compound microarray studies by Pickart and colleagues identified that GHK-Cu modulates over 4,000 human genes, including upregulation of tissue repair genes and downregulation of inflammatory and cancer-associated pathways

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Furthermore, these enzymes showed moderate stability toward pancreatic proteases and acid exposure, but their proteolytic capabilities were completely inactivated by pepsin, requiring their protection from gastric acid and pepsin