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In addition, it inhibits inflammation and carcinogenesis, reinforces the colonic defense barrier, modulates gut epithelium permeability, promotes satiety, increases sodium and water reabsorption (anti-diarrheal agent) and reduces oxidative stress 4

doi: 10.1093/oxfordjournals.aje.a010141 253 AshiqueSKumarSHussainAMishraNGargAGowdaBHJet al

While no published data specifically measures the combined risk, the theoretical concern is straightforward: two independent risk factors for the same serious condition are unlikely to be safer together