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L-tyrosine is the precursor to catecholamines, a group of neurotransmitters that play a central role in focus, motivation, and stress response

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In addition, at later stages of pluripotency, -KG derived from glutamine can promote early differentiation, suggesting that the stage of cellular maturity can alter the effect of -KG 105

Berberine has been shown to inhibit cancer cell proliferation by upregulating LDL receptors and inhibiting lipid synthesis pathways, such as fatty acid synthase, through activation of the AMPK pathway, which reduces cholesterol and lipid accumulation in tumor cells (82)