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Unnatural amino acids: Promising implications for the development of new antimicrobial peptides

Here we present the cryo-electron microscopy structure of Cdiff RNA polymerase in complex with fidaxomicin and identify a crucial fidaxomicin-binding determinant of Cdiff RNA polymerase that is absent in most gut microbiota such as Proteobacteria and Bacteroidetes

Currently, there are no effective treatments for NASH , but a recent study found that vitamin B12 and folate could help reduce inflammation and scarring in human subjects and animal models