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Plaque VSMCs show relatively short telomeres, elevated p16 and p21 levels, increased SA--gal activity, and enhanced oxidative stress compared to normal VSMCs [55]

10.1002/biof.1699 [DOI] [PubMed] [Google Scholar] 20.Daily JW, Kang S, Park S

N Engl J Med 1997;337:5818.PubMed 15

GSH is a low molecular weight compound which plays the role of a reductant to prevent thiol groups from getting oxidized, and react with detrimental ROS members like 1 O 2 and OH