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SKU: 61008758803
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In ARDS patients, macrophages secrete CXCL8 (IL-8) to activate a circulating neutrophil recruitment cascade via C-X-C chemokine receptor 1 (CXCR1) receptors

We next assessed if alkyne-HNE can bind to NLRP3 by treating THP-1 macrophages with 3 M HNE or 10 M alkyne-HNE after inflammasome activation by nigericin