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From genomic modeling to pathway modeling to network biology in breast cancer, AI-based biomarker research from pathological slides, prognostic research, target screening, drug repurposing in drug discovery research in breast cancer, computational methods have completely changed the research in breast cancer

: Cangiano C, Laviano A, Del Ben M, Preziosa I, Angelico F, Cascino A, Rossi-Fanelli F

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Alterations in aerobic metabolism have been reported in fibroblasts involved in pulmonary fibrosis [166], particularly increased glycolysis, resistance to apoptosis, and propensity to develop a metabolic-driven fibrotic phenotype, which appears to be linked to decreased ATP synthesis and increased mtROS production [169, 170]