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Endothelial and angiogenesis studies Endothelial cell models allow us to assess whether a variant ARG retains the signaling profile associated with VEGFR2, Akt and eNOS, or differs in the rate of peptide recovery from solid material and exposure parameters

Physical Symptoms of Vitamin B12 Deficiency Fatigue and weakness Pale skin Shortness of breath Nerve problems Mouth ulcers Digestive issues Vision problems Mobility difficulties Cognitive Symptoms of Vitamin B12 Deficiency Peripheral Neuropathy Cognitive Disturbances Memory Problems Reversible Dementia Confusion Decreased Problem Solving Psychiatric Symptoms of Vitamin B12 Deficiency Depression Anxiety Intrusive Thoughts Irritability Psychosis Inattention Insomnia Panic attacks Treatment of Vitamin B12 Deficiency It has been observed that oral administration of high-dose vitamin B12 (1 to 2 mg daily) is as effective as intramuscular administration for correcting anemia and neurologic symptoms

Some individuals may also experience mild systemic reactions like sneezing, nasal congestion, or fatigue

Physiol Rev