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Ser1177 phosphorylation also increases the Ca 2+ sensitivity of the synthase, permitting CaM binding and enzyme activation at lower intracellular Ca 2+ levels (Tran et al., 2009

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The differential responses to lithium may be partially explained by TPH2 (tryptophan hydroxylase 2) whose expression is known to be downregulated by lithium [79]

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da Fonseca, L., V

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Diabetes 52 : 24832489 Mauras N et al

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