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doi: 10.1007/s12011-022-03304-5 21 HeF.YinZ.WuC.XiaY.WuM.LiP.et al

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Excessive mitophagy leads to the removal of large numbers of mitochondria, resulting in the release of large amounts of iron, ROS, and lipid peroxidation from the mitochondria, which activates multiple ROS-induced cell death pathways, including ferroptosis [54, 55]