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Warburg and von Euler-Chelpin clarified the pathway in yeast, while Embden and Meyerhof did so in muscle tissue during the 1930s

For example, in epilepsy, KD provides epilepsy protection by increasing the relative abundance of Akkermansia and Parabacteroides and by increasing the ratio of Bacteroidetes / Firmicutes , similarly, transplantation of KD-associated gut microbiota and treatment with Akkermansia and Parabacteroides also provide epilepsy protection in control mice (223, 224)

Cells were seeded at a density of 2000-4000 cells per well in 96-well microtiter plates and subjected to various concentrations of the indicated drugs for 96h

Massa NML, Silva AS, de Oliveira CVC, Costa MJC, Persuhn DC, Barbosa CVS, et al