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10.1111/jpn.12104 207

Intranasal delivery of peptides to the brain relies primarily on extracellular passive transport from the olfactory region of the nasal cavity [17, 18, 19]

So, we also get into the importance of research and why it is important when you are exploring in the supplement world to know the research behind these various supplements and also how do you determine what is a quality supplement because it may differ from manufacturer to manufacturer