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Activation of nrf2 by sulforaphane inhibits high glucose-induced progression of pancreatic cancer via AMPK dependent signaling

The resulting Ca + overload disturbs ion homeostasis and induces mitochondrial dysfunction, oxidative stress, and neuronal edema, ultimately culminating in cell death ( Studies have shown that RIPreC significantly reduces glutamate levels in both the ischemic core and penumbra, mainly through the enhanced efflux of glutamate into peripheral blood

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