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Given its effect at promoting wakefulness and attention, it will come as no surprise that histaminergic neuronal firing rates are highest during waking hours and low or silent during sleep (Takahashi et al., 2006

The key comparison was between the KC group (KD with biotin) and the KBD group (KD without biotin), which allowed the researchers to assess whether KD alone increases biotin requirements or accelerates the development of biotin deficiency

Aflatoxin B1 inhibited autophagy flux by inducing lysosomal alkalinization in HepG2 cells

A complete understanding of the specific role of Wnt/-catenin in disease occurrence and progression can help guide the accurate use of these small-molecule drugs to maximize their efficacy and benefit more patients