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Results Characterization of human induced pluripotent stem cells Fifteen individual human iPSC lines were characterized and differentiated into HLCs with both the GF and SM protocol

Human studies have linked rs17782313, which lies near MC4R, to higher BMI, impaired satiation, and increased energy intake, and experimental work suggests that amylins anorectic effects intersect with melanocortin pathways that include MC4R signaling

If the methyl cycle in these patients could be rewired to prevent S-adenosylhomocysteine build-up, it would protect them from AHCY deficiency

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