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According to manufacturer studies, this ingredient has demonstrated the following benefits: Visible anti-wrinkle effect around the eye area (in vivo) Enhanced colony-forming efficiency of epidermal stem cells (in vitro) Improved ability of skin cells to regenerate and build new tissues in a 3D epidermis model (in vitro) Increased skin density (in vitro) Boosted vitality of epidermal stem cells (in vitro) Reversal of cellular aging signs in fibroblasts (in vitro) Centella Asiatica Extract (Centella) is one of the most researched botanical extracts in skincare with decades of studies backing its effects on inflammation, collagen, and the skin barrier

doi: 10.3389/fphys.2018.00477 27 XuJet al

Asparagine signals mitochondrial respiration and can be targeted to impair tumour growth

Melanocytes, through exosomes, communicate stress to the innate immune system, especially to dendritic cells that present antigens to T lymphocytes