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Zhang Y, Chen S, Wei J, Jiang J, Lin X, Wang Y, Hao C, Wu W, Yuan Z, Sun J, et al

Principal Investigator on A Double-Blind, Randomized, Parallel-Group Study with Quetiapine Extended Release as Comparator to Evaluate the Efficacy and Safety of Seltorexant 20 mg as Adjunctive Therapy to Antidepressants in Adult and Elderly Patients with Major Depressive Disorder with Insomnia Symptoms Who Have Responded Inadequately to Antidepressant Therapy. (Janssen)

In summary, while both oral and IN delivery require careful yet distinct considerations of formulation, IN delivery provides a viable alternative for drugs, especially those targeting the CNS

However, persistent cloudiness, visible particles, clumps, stringy material or a gel like texture may indicate that the peptide has not formed a uniform solution