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"A synthetic hexapeptide (Argireline) with antiwrinkle activity." Int J Cosmet Sci 24(5): 303-310

B-12 deficiency has also been linked to migraine headaches and menstrual irregularities. Recent research has shown that higher levels of Vitamin B-12 protect against brain changes that happen with aging.People with higher B-12 levels, even those without actual deficiency showed less age-related decline like dementia and Alzheimers disease

Cells were seeded into 96-well plates at 5000 cells per well and incubated at 37 C with 5% CO 2 for 24 h before treatment