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doi: 10.1126/scisignal.abj8393 43 BhatSMBadigerVAVasishtaSChakrabortyJPrasadSGhoshSet al

In this review, we will revisit the traditional roles of NADPH in inflammatory and anti-inflammatory pathways and highlight studies that reveal the competition for its consumption between these opposing pathways as a way to regulate inflammation in myeloid cells

The stability of the radical arises from the steric hindrance around the first-order divalent nitrogen atom and the "pushpull" effect between the second-order diphenylamino group as an electron donor and the picryl group as an electron acceptor