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For instance, the observed mitigation of microgliosis and pro-inflammatory cytokine release could be directly investigated by co-culturing our hCiPSC-NSCs or their conditioned medium with activated microglial cells (e.g., BV-2 cell line or primary microglia stimulated with LPS/ATP)

doi: 10.3390/ijms20061305 76 Hurtado-NuezGECorts-RojoCSnchez-CejaSGMartnez-FloresHESalgado-GarcigliaRBartolom-CamachoMCet al

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(5) Stier H, Vos E, Kenley D, Safety and Tolerability of the Hexadecapeptide AOD9604 in Humans