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(Biochem Pharmacol 2018) documented a reduction of -35% in white adipose tissue, -40% in adipocyte volume, -5.1% in body weight and -30% in plasma cholesterol in just 11 days in obese mice (DIO), without any change in food intake

J Pediat Gastroenterol Nutrit

Transcriptomic data also indicated the upregulated pathways associated with tight junctions and extracellular matrix (ECM) receptor interactions in skin tissues after LP-EVs treatment, which suggest an improvement in skin barrier function, a change that is also evident in the mouse ear following LP-EVs treatment

doi: 10.1016/j.ijporl.2010.09.022 9 ArifinA