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Interestingly, tBHQ, which is a compound added to foods and cosmetics as a preservative, induces Nrf2 and robustly increase xCT protein levels.[ref] Considering that increasing xCT can cause more glutamate in the synapse, it makes sense that this preservative is linked to ADHD and hyperactivity in some children.[ref] Regulation of Glutamate Transporter Levels: The availability of glutamate transporters in astrocytes and other glial cells depends on a number of different factors