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As explained below, strategies aiming at identifying physiological substrates/ligands have been recently developed for other GSTs and they should be applied to GHRs

2.1 Anti-chronic neuroinflammatory effects of EGCG Neuroinflammation serves as a protective mechanism within the nervous or central nervous system (CNS) against various threats including infections, toxic metabolites, autoimmunity, and traumatic brain injury, with the aim of eliminating harmful substances and damaged tissues (42)

62,63 Excess iron is stored in unstable iron pools, which can increase due to metabolic imbalance, leading to increased ROS production through Fenton reactions

There is a discrepancy between the production and lysis of MYFs, leading to surplus collagen deposition