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Folic acid supplement use and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a case-control study

en cas de dficit en B12, le MthylTHF saccumule ( pig ) et ne peut tre reconverti en THF, ce qui dclenche le fameux pige aux folates

Inclusion criteria: all participants must: be 65 years of age be attending a primary healthcare centre for consultation on some medical matter provide their informed consent to be included have a serum B12 concentration of 200 pg/ml at 4 months in over 70% of patients

As more researchers develop an interest in 5-amino-1MQ, clear dosing guidelines could greatly facilitate its application in experimental settings