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(5) Identification of the Rebate Period CPI-U As specified in section 1847A(i)(3)(F) of the Act, at 427.302(f), we proposed to codify the policy described in section 50.6 of the revised Medicare Part B Drug Inflation Rebate Guidance, that the rebate period CPI-U means the greater of the benchmark period CPI-U index level and the CPI-U index level for the first month of the calendar quarter that is 2 calendar quarters prior to the applicable calendar quarter in which the Part B rebatable drug is furnished

In cI, cleavage of NDUFS1 by caspase-3 inhibits cI activities, causing ROS production and collapse of mitochondria membrane potential