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& Freeman, L

& Pile, L

doi:10.1002/(SICI)1097-0177(199901)214:1 3.0.CO;2-X

Iron overload is the result of synergistic action of multiple pathways, with the central mechanism being excessive iron uptake mediated by transferrin receptor (TfR) and divalent metal transporter 1 (DMT1) (Lane et al