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CagriSema Reduces Blood Pressure in Adults With Overweight or Obesity: REDEFINE 1 Hypertension CagriSema Did Not Meet Primary End Point of Noninferiority to Tirzepatide Drug Topics Cagrilintidesemaglutide (CagriSema) versus semaglutide or cagrilintide in people with type 2 diabetes (REIMAGINE 2): a double blind, randomised, controlled, phase 3 study The Lancet Diabetes & Endocrinology Novo Nordisk's CagriSema 2.4 mg 2.4 mg demonstrated significant reduction in HbA1c and weight across multiple studies in the REIMAGINE program presented at ADA 2026

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