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Supportive Therapies To maximize AOD-9604s metabolic benefits, consider integrating: Structured nutrition protocols: Moderate caloric deficit (15-20% below maintenance), adequate protein intake (0.8-1.2 g/lb body weight) to preserve lean mass, strategic carbohydrate timing around training, and whole-food focused diet to support overall metabolic health

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Focus on consistent administration, appropriate dosing, and complementary nutrition and exercise strategies rather than injection site selection for optimal fat targeting results

Yet a poorly understood enzyme called NNMT (nicotinamide N-methyltransferase) actively depletes NAD+, converting it into inactive methyl-NAD compounds