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In addition, intracellular copper is preferentially trafficked as Cu(I)chaperone complexes to prevent the accidental release of free copper (Hofmann et al

5961 For example, estrone has less affinity for ER and ER and is more rapidly dissociated from the ERs than 17-estradiol

Collected pellets (containing PLGA nanoparticles) and supernatant (containing leached AuNCs as they do not sediment at this centrifugation conditions) were analyzed using ICP-MS