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[ 247 ] In esophageal squamous cell carcinoma, BACH1 renders CDH2, SNAI2, and VIM's upregulation by directly targeting their promoter regions, promoting the process of EMT

CHOP (by 17.8%, 40.3%, 46.6%, 56.7%, and 66.5%, respectively) (Fig

These examples point to an intriguing link between mtDNA or gene expression and depression, though more work needs to be done in this area, particularly to identify gene alterations in tissue from human patients