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There, it undergoes a two-step proteolytic cleavage by site-1 protease (S1P) and S2P

When the binding capacity is exceeded, bilirubin diffuses into the tissues

This work was supported by grants from the NIH/NCI (R37-CA230042) to G.M.D, the Ludwig Center at Harvard to I.S.H., the AACR-Takeda Oncology Lung Cancer Research Fellowship (19-40-38-KANG) to Y.P.K., a National Pancreas Foundation grant to C.J

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