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Description

In contrast to primary GBMs, TP53 mutations associated with methylation of the MGMT promoter are observed in most secondary GBMs, along with partial loss of heterozygosity of 10q, 13q, 19q, and 22q (4)

The single-session price is the first conversation

The typical maintenance dose is 1,000 mcg administered IM once monthly

Patients should be offered genetic testing if they have a personal or family history of intrahepatic cholestasis, such as PFIC, BRIC, ICP, and LPAC combined with drug at-cholestasis risk use [20] (Fig