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One trial found that both pregabalin and duloxetine improved patient-reported CIPN symptoms, with 150 mg of pregabalin performing better than 60 mg of duloxetine (Salehifar 2020)

This formulation has significant advantages in that it improves the bioavailability of the product and its speed of action , Glutathione being already in an active form and ready to oxidize when needed to perform its protective function

This informs whether peptide therapy, testosterone replacement or a combination may be most appropriate

Decrease in catalase (CAT) activity and expression inhibition of respiratory chain complexes I and III were partially restored