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94 The role of ATM as a sensor of oxidative stress suggests a novel function independent of DNA damage repair that is crucial for preventing DNA damage under oxidative stress conditions

Meanwhile, we must also take into account that the amino - acid metabolic profiles we observed are likely to be affected by a multitude of factors, such as genetic predispositions, environmental exposures, and dietary habits

First of all, they rely on catalytic protein removal instead of inhibiting activity to degrade undruggable proteins