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Doses Per Vial Vial duration varies by dose escalation phase: 3mg vial: At 0.25mg/week = 12 weeks At 0.5mg/week = 6 weeks At 1mg/week = 3 weeks At 2.4mg/week = 1.25 weeks 5mg vial: At 0.25mg/week = 20 weeks At 0.5mg/week = 10 weeks At 1mg/week = 5 weeks At 1.7mg/week = ~3 weeks At 2.4mg/week = ~2 weeks A 5mg vial can cover the entire first 4 months of a slow escalation protocol starting at 0.25mg

10.1002/jat.3780 38 MeerschM.KllmarM.SchmidtC.GerssJ.WeinhageT.MargrafA.et al (2018)

Its important to watch closely and teach patients about these risks

(2018) protocol, several behaviors were observed to measure fish aggression, comprising the straight movement of one fish toward another (approach), the rate at which fish swim rapidly after one another (chasing), fishes escaping from the adversary by swimming (fleeing), the rate at which two fish stand with their mouths open against one another (mouth pushing), and all of a fishs fins extend out or expand (spreading of fins)