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Increasing evidence suggests that soluble A oligomers, rather than insoluble plaques, are major contributors to synaptic dysfunction and cognitive decline in AD, although their precise pathogenic role remains under active investigation and debate (Selkoe, 2008

Vitamin B12, a water-soluble vitamin, plays a crucial role in various bodily functions, including the formation of red blood cells, neurological function, and energy metabolism

Helps regulate the nervous system: B12 supports a healthy mood, reduced stress and decreased feelings of anxiety

Given the short half-life, twice-daily dosing provides additional exposure compared to once-daily protocols at the same total dose