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doi: 10.3389/fphar.2026.1694895 Received 29 August 2025 Revised 30 November 2025 Accepted 12 January 2026 Published 13 February 2026 Volume 17 - 2026 Edited by Ji Yichun, University of California, San Diego, United States Reviewed by Janina P

Similar content being viewed by others Introduction Sulfur is a crucial microelement for plant nutrition, required by the biosynthesis of sulfolipids, antioxidants, cofactors, secondary metabolites, and amino acids that are strictly or conditionally essential for human nutrition (cysteine and methionine) 1, 2

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808 On the other hand, mass spectrometry has the advantage of detecting very low concentrations of metabolites but often lacks reproducibility due to the influence of various ions or proteins in the samples and cannot be directly used for in vivo detection