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Ongoing side effects at maintenance tend to be mild and manageable, primarily consisting of reduced appetite (which is the intended effect) and occasional mild nausea that comes and goes

Oral administration of high-dose vitamin B 12 (1 to 2 mg daily) is considered as effective as intramuscular administration for correcting anemia and neurologic symptoms Despite many studies suggesting oral administration of vitamin B 12 to be easy, effective and less costly than intramuscular administration, debate surrounds the effectiveness of the oral route

Hematoxylin and eosin (H&E) staining results showed that CDCZA treatment caused the most obvious nuclear pyrosis, fragmentation and nucleolysis, and normal morphology of cell membrane and nucleus could not be seen (Fig

doi: 10.1158/1078-0432.CCR-12-3891